Department of Pharmacy

Drug delivery

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Drug absorption, distribution and delivery

We wish to understand drug absorption at the molecular and cellular level in order to deliver drugs more effectively via the oral route. We also focus on the distribution and function of important drug-transporting proteins in the human body in order to better understand drug disposition and drug interactions.

We take a multidisciplinary approach and combine computational chemistry and bioinformatics with cell- and molecular biology, biopharmaceutics, pharmaceutics and physical chemistry to find new ways to predict oral drug absorption, to define rate-limiting barriers to the absorption and organ distribution of different types of drugs and to characterize drug transport routes across organ barriers in important pharmacokinetic organs such as the intestine, liver and kidney.

We anticipate that our research will provide insights into new mechanisms for drug absorption, disposition and delivery, and, hopefully, suggest new therapeutic strategies for efficient oral drug delivery.

Main research areas


Contact

Per Artursson
Maria Karlgren
Pär Matsson